A POPULATION STUDY TO IDENTIFY FRACTURE RISK IN LIVERPOOL, ENGLAND

BACKGROUND: Fractures are in most cases treated by Accident and Emergency (A&E) departments and they have a substantial financial impact on health budgets. The epidemiology of fractures in the Liverpool city region has not been systematically investigated in recent years. This study aims to address this issue by providing valuable data that could aid in the design of fracture prevention strategies. METHODS: Population fracture data was collected by the Liverpool Primary Care Trust between February 2009 and July 2010, accounting for the majority of fractures registered in the city. The data was sorted by type, age, sex and upper/lower body in order to observe patterns in different groups. RESULTS: The data highlighted a significant difference between the sexes where anatomical sites varied greatly. Females suffer from fractures of the femur and the arm bones in a higher frequency, while males exhibit their highest fracture rates in the femur, lower arm and hand and craniofacial regions. Women also tend to have fractures later in life while most men fracture bones earlier. CONCLUSION: This finding corresponds with numerous sources in the medical literature. The present work supports the development of strategies designed to reduce fractures in specific age groups

First record of the wood-boring beetles Oxymirus cursor and Sinodendron cylindricum in Greece

Δύο είδη ξυλοφάγων κολεοπτέρων καταγράφηκαν για πρώτη φορά στην Ελλάδα. Στα τέλη του Ιουνίου 2001, το είδος Oxymirus cursor (L.) (Coleoptera: Cerambycidae) της φυλής Oxymirini βρέθηκε στο όρος Ροδόπη, ενώ στις αρχές Αυγούστου 2012 το είδος Sinodendron cylindricum (L.) (Coleoptera: Lucanidae) της φυλής Sinidendrini βρέθηκε στο όρος Φαλακρό, στη Β. Ελλάδα. Παρουσιάζονται εικόνες των δύο ειδών καθώς και πληροφορίες σχετικά με την εξάπλωση τους, την βιολογία και οικολογία τους.Two wood-boring beetles are recorded for the first time in Greece. On late June 2001, the lepturine longicorn beetle Oxymirus cursor (L.) (Coleoptera: Cerambycidae) was found on Mt. Rodopi, and on early August 2012 the lucanid beetle Sinodendron cylindricum (L.) (Coleoptera: Lucanidae) was found on Mt. Falakron, in N. Greece. Images of both species and information on their distribution, ecology and biology, are presented

Automated detection and monitoring of grain beetles using a “smart” pitfall trap: Poster

A smart, electronic, modified pitfall trap, for automatic detection of adult beetle pests inside the grain mass is presented. The whole system is equipped with optoelectronic sensors to guard the entrance of the trap in order to detect, time-stamp, and GPS tag the incoming insect. Insect counts as well as environmental parameters that correlate with insect’s population development are wirelessly transmitted to a central monitoring agency in real time, are visualized and streamed to statistical methods to assist effective control of grain pests. The prototype trap was put in a large plastic barrel (120lt) with 80kg maize. Adult beetles of various species were collected from laboratory rearings and transferred to the experimental barrel. Caught beetle adults were checked and counted after 24h and were compared with the counts from the electronic system. Results from the evaluation procedure showed that our system is very accurate, reaching 98-99% accuracy on automatic counts compared with real detected numbers of adult beetles inside the trap. In this work we emphasize on how the traps can be selforganized in networks that collectively report data at local, regional, country, continental, and global scales using the emerging technology of the Internet of Things (IoT). We argue that smart traps communicating through IoT to report in real-time the level of the pest population from the grain mass straight to a human controlled agency can, in the very near future, have a profound impact on the decision making process in stored grain protection.A smart, electronic, modified pitfall trap, for automatic detection of adult beetle pests inside the grain mass is presented. The whole system is equipped with optoelectronic sensors to guard the entrance of the trap in order to detect, time-stamp, and GPS tag the incoming insect. Insect counts as well as environmental parameters that correlate with insect’s population development are wirelessly transmitted to a central monitoring agency in real time, are visualized and streamed to statistical methods to assist effective control of grain pests. The prototype trap was put in a large plastic barrel (120lt) with 80kg maize. Adult beetles of various species were collected from laboratory rearings and transferred to the experimental barrel. Caught beetle adults were checked and counted after 24h and were compared with the counts from the electronic system. Results from the evaluation procedure showed that our system is very accurate, reaching 98-99% accuracy on automatic counts compared with real detected numbers of adult beetles inside the trap. In this work we emphasize on how the traps can be selforganized in networks that collectively report data at local, regional, country, continental, and global scales using the emerging technology of the Internet of Things (IoT). We argue that smart traps communicating through IoT to report in real-time the level of the pest population from the grain mass straight to a human controlled agency can, in the very near future, have a profound impact on the decision making process in stored grain protection

Reproductive efficiency of the bethylid wasp Cephalonomia tarsalis: the influences of spatial structure and host density

The parasitoid wasp Cephalonomia tarsalis (Ashmead) (Hymenoptera: Bethylidae) is commonly present in stored product facilities. While beneficial, it does not provide a high 24 degree of biological pest control against its host, the saw-toothed beetle Oryzaephilus surinamensis (L.) (Coleoptera: Silvanidae). A candidate explanation for poor host population suppression is that adult females interfere with each other’s foraging and reproductive behavior. We used simple laboratory microcosms to evaluate such mutual interference in terms of its overall effects on offspring production. We varied the density of the hosts and also the spatial structure of the environment, via the extent of population sub-division and the provision of different substrates. Production of C. tarsalis offspring was positively influenced by host density and by the isolation of females. With incomplete sub-division within microcosms offspring production was, in contrast, low and even zero. The provision of corrugated paper as a substrate enhanced offspring production and partially mitigated the effects of mutual interference. We recommend simple improvements to mass rearing practice and identify promising areas for further behavioral and chemical studies towards a better understanding of the mechanisms of mutual interference

Expression of the Tpl2/Cot oncogene in human T-cell neoplasias

BACKGROUND: Tpl2/Cot oncogene has been identified in murine T-cell lymphomas as a target of MoMuLV insertion. Animal and tissue culture studies have shown that Tpl2/Cot is involved in interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) production by T-cells contributing to T-cell proliferation. In the present report we examined a series of 12 adult patients with various T-cell malignancies, all with predominant leukemic expression in the periphery, for the expression of Tpl2/Cot oncogene in order to determine a possible involvement of Tpl2/Cot in the pathogenesis of these neoplasms. RESULTS: Our results showed that Tpl2/Cot was overexpressed in all four patients with Large Granular Lymphocyte proliferative disorders (LGL-PDs) but in none of the remaining eight patients with other T-cell neoplasias. Interestingly, three of the LGL-PD patients displayed neutropenia, one in association with sarcoidosis. Serum TNF-α levels were increased in all Tpl2/Cot overexpressing patients while serum IL-2 was undetectable in all subjects studied. Genomic DNA analysis revealed no DNA amplification at the Tpl2/Cot locus in any of the samples analyzed. CONCLUSIONS: We conclude that Tpl2/Cot, a gene extensively studied in animal and tissue culture T-cell models may be also involved in the development of human LGL-PD and may have a role in the pathogenesis of immune manifestations associated with these diseases. This is the first report implicating Tpl2/Cot in human T-cell neoplasias and provides a novel molecular event in the development of LGL-PDs

Analysis of clonality and antibiotic resistance among early clinical isolates of Enterococcus faecium in the United States.

BACKGROUND: The Enterococcus faecium genogroup, referred to as clonal complex 17 (CC17), seems to possess multiple determinants that increase its ability to survive and cause disease in nosocomial environments. METHODS: Using 53 clinical and geographically diverse US E. faecium isolates dating from 1971 to 1994, we determined the multilocus sequence type; the presence of 16 putative virulence genes (hyl(Efm), esp(Efm), and fms genes); resistance to ampicillin (AMP) and vancomycin (VAN); and high-level resistance to gentamicin and streptomycin. RESULTS: Overall, 16 different sequence types (STs), mostly CC17 isolates, were identified in 9 different regions of the United States. The earliest CC17 isolates were part of an outbreak that occurred in 1982 in Richmond, Virginia. The characteristics of CC17 isolates included increases in resistance to AMP, the presence of hyl(Efm) and esp(Efm), emergence of resistance to VAN, and the presence of at least 13 of 14 fms genes. Eight of 41 of the early isolates with resistance to AMP, however, were not in CC17. CONCLUSIONS: Although not all early US AMP isolates were clonally related, E. faecium CC17 isolates have been circulating in the United States since at least 1982 and appear to have progressively acquired additional virulence and antibiotic resistance determinants, perhaps explaining the recent success of this species in the hospital environment